RNU6-401P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-401P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU6-401P data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher RNU6-401P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-401P expression acts as an unfavorable survival marker.

DLBC, LIHC, and ESCA are the cancer types where RNU6-401P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
DLBCOSTertileII,III,IV0.0990.731.00590view →
LIHCOSTertileAll0.2040.777.00845view →
ESCAOSTertileAll0.1980.872.00336view →
BRCADFSTertileAll0.1401.000.00136view →
LGGDFSTertileAll0.0890.845<.00112view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration