RNU6-397P

Across TCGA patient cohorts, RNU6-397P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,663 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-397P-associated GO terms across cancer lineages are Mitochondrial outer membrane permeabilization, Regulation of protein localization to cell periphery, and Mitochondrial membrane organization. Each is linked with RNU6-397P in more than 5 cancer types. Because this analysis shows association rather than direction, both RNU6-397P-to-partner and partner-to-RNU6-397P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial outer membrane permeabilization grouped by RNU6-397P-low versus RNU6-397P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-397P→partner) and Y-score (partner→RNU6-397P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial outer membrane permeabilization →	+0.143	+0.136	<.001	<.001	3	6
STAD	Regulation of protein localization to cell periphery →	+0.132	+0.122	<.001	<.001	3	6
STAD	Mitochondrial membrane organization →	+0.162	+0.138	<.001	<.001	3	6
STAD	Negative regulation of protein secretion →	+0.087	+0.112	<.001	<.001	3	6
ESCA	Response to increased oxygen levels →	+0.148	+0.223	<.001	.001	3	6
ESCA	Reactive oxygen species metabolic process →	+0.109	+0.282	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,663 associations by consensus.

Mitochondrial outer membrane permeabilization by RNU6-397P expression — STAD

Explore this box plot interactively →