RNU6-390P

Across TCGA patient cohorts, RNU6-390P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,559 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-390P-associated GO terms across cancer lineages are Cellular response to glucocorticoid stimulus, Positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway, and Substrate adhesion-dependent cell spreading. Each is linked with RNU6-390P in more than 6 cancer types. Because this analysis shows association rather than direction, both RNU6-390P-to-partner and partner-to-RNU6-390P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to glucocorticoid stimulus grouped by RNU6-390P-low versus RNU6-390P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-390P→partner) and Y-score (partner→RNU6-390P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Cellular response to glucocorticoid stimulus →	+0.097	+0.234	<.001	<.001	3	7
STAD	Positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway →	+0.088	+0.104	<.001	<.001	3	6
STAD	Substrate adhesion-dependent cell spreading →	+0.103	+0.086	<.001	<.001	3	6
ESCA	Cell cycle G1/S phase transition →	+0.104	+0.217	<.001	.002	3	6
ESCA	Positive regulation of apoptotic signaling pathway →	+0.127	+0.227	<.001	.001	3	6
STAD	Hematopoietic or lymphoid organ development →	+0.093	+0.098	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,559 associations by consensus.

Cellular response to glucocorticoid stimulus by RNU6-390P expression — ESCA

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