RNU6-389P

Across TCGA pan-cancer cohorts, RNU6-389P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-389P data layer compared with 5 for mutation status.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher RNU6-389P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-389P expression acts as an unfavorable survival marker.

CESC, HNSC, and KICH are the cancer types where RNU6-389P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	III,IV	0.091	0.755	<.001	72	view →
HNSC	DFS	Tertile	III,IV	0.210	0.631	<.001	48	view →
KICH	OS	Tertile	All	0.155	0.926	<.001	39	view →
BLCA	DFS	Tertile	IV	0.183	0.473	.031	30	view →
LGG	DFS	Tertile	All	0.383	0.743	<.001	27	view →
BRCA	OS	Tertile	III,IV	0.144	0.556	<.001	24	view →
KIRC	DFS	Tertile	All	0.461	0.645	.004	24	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
KIRP	DFS	Tertile	III,IV	0.037	0.723	<.001	18	view →
LIHC	OS	Tertile	All	0.255	0.773	.012	18	view →
LUSC	OS	Tertile	IV	0.001	0.651	.025	18	view →
ESCA	OS	Tertile	IV	0.243	0.590	.046	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU6-389P–CESC (OS)

Open the CESC breakdown →