RNU6-386P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-386P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNU6-386P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-386P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-386P expression acts as an unfavorable survival marker.

HNSC, KIRC, and UCEC are the cancer types where RNU6-386P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSTertileAll0.1550.712<.00172view →
KIRCOSTertileII,III,IV0.2910.699.00854view →
UCECOSTertileIV0.3080.748.00936view →
BLCADFSTertileIII,IV0.1590.572.0369view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration