RNU6-381P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-381P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU6-381P data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RNU6-381P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-381P expression acts as an unfavorable survival marker.

OV, HNSC, and LUSC are the cancer types where RNU6-381P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVOSTertileII,III,IV0.1700.847<.001144view →
HNSCOSTertileII,III,IV0.0820.711<.00166view →
LUSCDFSTertileAll0.1580.648.00148view →
BRCADFSTertileAll0.1180.527<.00148view →
SKCMDFSTertileAll0.1700.737.00836view →
UCECDFSTertileAll0.1000.646.02436view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration