Across TCGA pan-cancer cohorts, RNU6-380P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-380P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU6-380P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-380P expression acts as an unfavorable survival marker.

UCEC, KIRC, and KICH are the cancer types where RNU6-380P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	0.208	0.771	<.001	120	view →
KIRC	DFS	Tertile	III,IV	0.093	0.755	<.001	84	view →
KICH	DFS	Tertile	All	0.102	0.848	.004	39	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	27	view →
SKCM	DFS	Tertile	All	0.037	0.729	<.001	27	view →
THCA	DFS	Tertile	All	0.676	0.911	.002	18	view →
GBM	DFS	Tertile	All	0.087	0.291	.025	9	view →
COAD	DFS	Tertile	All	0.285	0.693	.046	9	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

Exploration

Same gene, other analysis: RNU6-380P tumor-vs-normal RNA expression · all RNU6-380P data types