RNU6-366P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-366P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-366P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-366P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-366P expression acts as an unfavorable survival marker.

KIRC, STAD, and UVM are the cancer types where RNU6-366P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileIV0.2540.632.01060view →
STADDFSTertileAll0.3640.729.00154view →
UVMOSTertileAll0.2480.769.00736view →
ESCADFSTertileAll0.2440.519.00818view →
CESCOSTertileAll0.0950.585.03818view →
SKCMOSTertileIII,IV0.2020.697.0169view →
LIHCDFSTertileAll0.0340.554<.0019view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

Exploration