RNU6-365P

Across TCGA pan-cancer cohorts, RNU6-365P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-365P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-365P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-365P expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.

KIRC, ACC, and SKCM are the cancer types where RNU6-365P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.039	0.632	<.001	132	view →
ACC	DFS	Tertile	All	0.010	0.624	<.001	117	view →
SKCM	OS	Tertile	All	0.221	0.784	<.001	90	view →
UCS	OS	Tertile	III,IV	0.104	0.591	.004	90	view →
LIHC	OS	Tertile	II,III,IV	0.051	0.716	<.001	72	view →
MESO	DFS	Tertile	III,IV	0.061	0.423	<.001	54	view →
PRAD	DFS	Tertile	All	0.200	0.780	<.001	30	view →
LGG	DFS	Tertile	All	0.896	0.347	.002	15	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU6-365P–KIRC (DFS)

Open the KIRC breakdown →