RNU6-358P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-358P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-358P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-358P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-358P expression acts as an unfavorable survival marker, although some lineages such as LUSC and LAML show a favorable association.

KIRC, UVM, and UCS are the cancer types where RNU6-358P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSQuartileAll0.5140.662<.001174view →
UVMDFSTertileAll0.2610.771.00581view →
UCSDFSTertileIV0.2370.840<.00154view →
ACCOSTertileAll0.4460.810.00554view →
READDFSTertileAll0.2550.844.00445view →
PAADOSTertileII,III,IV0.3260.600.00339view →
STADOSTertileII,III,IV0.3460.606.01536view →
LUSCDFSTertileII,III,IV1.0000.569.01536view →
THYMDFSTertileAll0.2260.763.00215view →
CHOLDFSTertileAll0.0370.497.0049view →
SKCMOSTertileIV0.1790.727<.0019view →
LIHCDFSTertileIII,IV0.0940.424.0039view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU6-358P–KIRC (DFS)

Kaplan–Meier survival curve for RNU6-358P RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration