RNU6-344P

Across TCGA pan-cancer cohorts, RNU6-344P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-344P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-344P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-344P expression acts as an unfavorable survival marker, although some lineages such as LAML and LUSC show a favorable association.

MESO, KICH, and KIRC are the cancer types where RNU6-344P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	IV	0.036	0.602	<.001	72	view →
KICH	OS	Tertile	All	0.155	0.926	<.001	63	view →
KIRC	OS	Tertile	All	0.513	0.646	.007	54	view →
UCS	DFS	Tertile	III,IV	0.123	0.452	.004	36	view →
SKCM	OS	Tertile	All	0.149	0.344	.011	33	view →
LAML	DFS	Tertile	All	0.689	0.428	.003	30	view →
COAD	DFS	Tertile	III,IV	0.170	0.703	.004	27	view →
LUSC	DFS	Tertile	II,III,IV	0.883	0.680	.016	21	view →
TGCT	DFS	Tertile	All	0.307	0.710	.007	12	view →
BLCA	DFS	Tertile	III,IV	0.356	0.583	.016	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
LIHC	DFS	Tertile	II,III,IV	0.150	0.432	.037	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RNU6-344P–MESO (OS)

Open the MESO breakdown →