RNU6-338P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-338P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-338P data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher RNU6-338P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-338P expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

READ, OV, and ACC are the cancer types where RNU6-338P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
READDFSTertileAll0.1320.824<.00181view →
OVOSTertileIII,IV0.4230.685.01466view →
ACCOSTertileAll0.1330.686.00454view →
STADOSTertileIV1.0000.252.00839view →
KICHOSTertileAll0.1910.875.00136view →
THYMDFSTertileAll0.4160.895<.00136view →
LUADOSTertileII,III,IV0.2330.561.02627view →
SKCMOSTertileIII,IV0.1370.409.01224view →
THCADFSTertileII,III,IV0.4950.884.01821view →
KIRCDFSTertileIV0.3050.628.02118view →
LGGDFSTertileAll0.6600.837.02015view →
BLCADFSTertileAll0.4540.631.03212view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration