RNU6-319P

Across TCGA pan-cancer cohorts, RNU6-319P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-319P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-319P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-319P expression acts as an unfavorable survival marker, although some lineages such as ESCA and BLCA show a favorable association.

UVM, HNSC, and CESC are the cancer types where RNU6-319P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	III,IV	0.071	0.636	<.001	72	view →
HNSC	OS	Tertile	II,III,IV	0.177	0.716	<.001	54	view →
CESC	OS	Tertile	III,IV	0.182	0.686	.004	54	view →
THYM	OS	Tertile	All	0.558	0.895	<.001	48	view →
READ	DFS	Tertile	All	0.082	0.799	<.001	45	view →
KIRC	OS	Tertile	All	0.525	0.682	.016	42	view →
KICH	DFS	Tertile	III,IV	0.043	0.774	.005	36	view →
PAAD	OS	Tertile	All	0.177	0.601	<.001	36	view →
LUSC	OS	Tertile	All	0.170	0.407	.005	30	view →
ESCA	OS	Quartile	III,IV	0.720	0.286	.001	27	view →
LIHC	DFS	Tertile	All	0.145	0.537	.003	27	view →
GBM	DFS	Tertile	All	0.089	0.249	.006	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-319P–UVM (DFS)

Open the UVM breakdown →