RNU6-313P

Across TCGA pan-cancer cohorts, RNU6-313P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNU6-313P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNU6-313P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-313P is over-expressed in tumor, although a few such as KIRC and LIHC show the opposite, repressed pattern.

HNSC, KIRC, and BRCA are the cancer types where RNU6-313P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-313P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.218	.018	5	view →
KIRC	All	All	−0.100	.016	3	view →
BRCA	All	IV	+0.995	<.001	2	view →
PAAD	Male	All	+0.850	.013	2	view →
KICH	All	III,IV	+0.381	.036	2	view →
LIHC	Male	All	−0.067	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RNU6-313P–HNSC

Open the HNSC breakdown →