RNU6-306P

Across TCGA pan-cancer cohorts, RNU6-306P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-306P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-306P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-306P expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

KIRC, MESO, and HNSC are the cancer types where RNU6-306P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.485	0.657	<.001	141	view →
MESO	OS	Tertile	II,III,IV	0.062	0.569	<.001	135	view →
HNSC	DFS	Tertile	III,IV	0.142	0.392	.011	57	view →
THYM	DFS	Tertile	All	0.459	0.883	<.001	57	view →
BRCA	DFS	Tertile	IV	0.175	0.730	.005	54	view →
ACC	DFS	Tertile	All	0.078	0.634	.001	36	view →
LGG	DFS	Tertile	All	0.451	0.751	<.001	30	view →
OV	DFS	Tertile	IV	0.253	0.495	.022	24	view →
LUSC	OS	Tertile	III,IV	1.000	0.304	.034	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RNU6-306P–KIRC (OS)

Open the KIRC breakdown →