Across TCGA pan-cancer cohorts, RNU6-29P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-29P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNU6-29P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-29P is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH, THCA, and LIHC are the cancer types where RNU6-29P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-29P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	IV	−0.640	.004	4	view →
THCA	All	IV	+0.747	<.001	2	view →
LIHC	Male	II,III,IV	+0.192	.042	2	view →
PRAD	All	All	+0.151	.045	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-29P RNA expression & survival · all RNU6-29P data types