RNU6-296P

Across TCGA pan-cancer cohorts, RNU6-296P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-296P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-296P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-296P expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

MESO, LGG, and THYM are the cancer types where RNU6-296P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	All	0.182	0.403	<.001	108	view →
LGG	OS	Tertile	All	0.610	0.894	<.001	33	view →
THYM	OS	Tertile	All	0.352	0.884	<.001	24	view →
PAAD	OS	Tertile	All	0.400	0.662	.038	18	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
KIRP	DFS	Tertile	III,IV	0.268	0.742	.006	18	view →
READ	DFS	Tertile	All	0.162	0.720	.019	18	view →
HNSC	OS	Tertile	All	1.000	0.745	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU6-296P–MESO (DFS)

Open the MESO breakdown →