RNU6-295P

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNU6-295P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,780 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-295P-associated GO terms across cancer lineages are Positive regulation of telomere maintenance, Methylation, and Stress granule assembly. Each is linked with RNU6-295P in more than 4 cancer types. Because this analysis shows association rather than direction, both RNU6-295P-to-partner and partner-to-RNU6-295P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomere maintenance grouped by RNU6-295P-low versus RNU6-295P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-295P→partner) and Y-score (partner→RNU6-295P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAPositive regulation of telomere maintenance →+0.153+0.085<.001.00435
ESCAMethylation →+0.112+0.094<.001.00235
STADStress granule assembly →+0.139+0.165<.001<.00135
STADNucleoside phosphate biosynthetic process →+0.111+0.167<.001<.00135
ESCARegulation of double-strand break repair →+0.130+0.095<.001.00135
ESCAPositive regulation of double-strand break repair →+0.119+0.126<.001.00235
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,780 associations by consensus.

Positive regulation of telomere maintenance by RNU6-295P expression — ESCA

Box plot of Positive regulation of telomere maintenance in RNU6-295P-low vs RNU6-295P-high samples in ESCA.

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Exploration