RNU6-289P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-289P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-289P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-289P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-289P expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

HNSC, STAD, and CESC are the cancer types where RNU6-289P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileAll0.3200.670<.00190view →
STADDFSTertileAll0.2600.564<.00184view →
CESCDFSTertileIII,IV0.0910.728<.00178view →
SKCMDFSTertileAll0.2700.766<.00136view →
BLCADFSTertileIV0.1590.486.00236view →
ESCAOSTertileAll0.4750.712.00618view →
LAMLDFSTertileAll0.0270.583<.00118view →
LUSCDFSTertileII,III,IV0.8380.587.0229view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

Exploration