RNA, U6 small nuclear 288, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-288P profile across patient tissues and cancer cell-line models. RNU6-288P expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, RNU6-288P is differentially expressed in 8, with the highest sampling consensus in LUSC. Additionally, RNU6-288P RNA expression shows 9,637 significant gene co-expression associations, with the highest sampling consensus in LAML. Together, these results highlight HNSC, LUSC, and LAML as cancer lineages where RNU6-288P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-288P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-288P survival associations across molecular data types. RNU6-288P RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-288P RNA expression–survival associations across cancer types. High RNU6-288P expression shows unfavorable associations in KIRP and CESC, but favorable associations in HNSC, UCS, COAD and READ. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify HNSC as the clearest survival context for RNU6-288P RNA expression.
This table summarizes RNU6-288P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-288P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-288P shows higher tumor expression in LUSC, HNSC, BLCA, STAD, LUAD and KICH. The LUSC box plot shows higher RNU6-288P RNA expression in tumor versus normal tissue (log2 FC = +0.450, t-test p < 0.001).
This table shows molecular features associated with RNU6-288P in patient tissues and cancer cell lines. In patient samples, RNU6-288P shows the broadest associations at the RNA and protein expression levels, with LAML recurring as the lineage with the largest associated feature set.
