RNU6-285P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-285P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-285P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-285P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-285P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

SKCM, KIRC, and KICH are the cancer types where RNU6-285P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMDFSTertileIII,IV0.0530.648<.00163view →
KIRCDFSTertileAll0.7000.868.00460view →
KICHDFSTertileII,III,IV0.0430.950<.00154view →
STADDFSTertileIV0.0830.379.00136view →
BRCADFSTertileAll0.7840.907.00336view →
THYMOSTertileIII,IV0.2120.953.00927view →
ESCADFSTertileIII,IV0.5240.244.01921view →
BLCAOSTertileIII,IV0.0900.582<.00118view →
GBMOSTertileAll0.0050.416<.00118view →
LGGDFSTertileAll0.1840.734<.00118view →
THCADFSTertileAll0.6870.945.00512view →
PCPGOSTertileAll0.3120.970.01212view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

Exploration