RNU6-282P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-282P RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RNU6-282P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU6-282P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-282P is over-expressed in tumor.

KIRC, HNSC, and LUAD are the cancer types where RNU6-282P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-282P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleII,III,IV+0.474.0016view →
HNSCAllAll+0.258.0115view →
LUADFemaleAll+0.642.0014view →
READAllIII,IV+1.174<.0012view →
LUSCAllAll+0.426<.0012view →
LIHCAllAll+0.184.0012view →
CHOLAllAll+0.798.0301view →
ESCAFemaleAll+0.703.0281view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

Exploration