Across TCGA pan-cancer cohorts, RNU6-280P RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated RNU6-280P data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher RNU6-280P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-280P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

STAD, SKCM, and ESCA are the cancer types where RNU6-280P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	IV	0.075	0.496	.013	36	view →
SKCM	DFS	Tertile	All	0.169	0.730	<.001	21	view →
ESCA	OS	Tertile	III,IV	1.000	0.372	.033	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RNU6-280P tumor-vs-normal RNA expression · all RNU6-280P data types