RNU6-27P

Across TCGA pan-cancer cohorts, RNU6-27P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-27P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU6-27P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-27P expression acts as an unfavorable survival marker.

KICH, MESO, and BRCA are the cancer types where RNU6-27P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.082	0.877	<.001	57	view →
MESO	OS	Tertile	All	0.130	0.557	.019	54	view →
BRCA	DFS	Tertile	All	0.367	0.531	<.001	48	view →
BLCA	OS	Tertile	All	0.108	0.451	.008	42	view →
LGG	DFS	Tertile	All	0.609	0.839	<.001	33	view →
THCA	DFS	Tertile	III,IV	0.145	0.765	.003	9	view →
STAD	DFS	Quartile	IV	0.097	0.416	.017	6	view →
SKCM	OS	Tertile	All	0.644	0.881	.001	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU6-27P–KICH (OS)

Open the KICH breakdown →