Across TCGA pan-cancer cohorts, RNU6-275P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU6-275P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNU6-275P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-275P is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC and LUAD are the cancer types where RNU6-275P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-275P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.090	.025	2	view →
LUAD	All	II,III,IV	−0.173	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RNU6-275P RNA expression & survival · all RNU6-275P data types