RNU6-274P

Across TCGA pan-cancer cohorts, RNU6-274P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-274P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-274P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-274P expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

BLCA, SKCM, and UCEC are the cancer types where RNU6-274P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.051	0.720	<.001	144	view →
SKCM	DFS	Tertile	II,III,IV	0.216	0.687	<.001	57	view →
UCEC	DFS	Tertile	All	0.100	0.649	<.001	54	view →
LAML	DFS	Tertile	All	0.027	0.583	<.001	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
BRCA	DFS	Tertile	II,III,IV	0.321	0.889	<.001	18	view →
ESCA	OS	Tertile	II,III,IV	0.105	0.867	.016	18	view →
HNSC	DFS	Tertile	All	1.000	0.309	.031	9	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU6-274P–BLCA (OS)

Open the BLCA breakdown →