RNU6-273P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-273P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-273P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU6-273P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-273P expression acts as an unfavorable survival marker.

UCEC, BRCA, and HNSC are the cancer types where RNU6-273P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSTertileAll0.6650.879<.001120view →
BRCADFSTertileAll0.1401.000.00172view →
HNSCOSTertileII,III,IV0.2010.600.01836view →
DLBCOSTertileIII,IV0.2721.000.01728view →
THYMDFSTertileAll0.0750.885<.00124view →
BLCAOSTertileIV0.0510.600<.00118view →
ESCADFSTertileAll0.1480.673.04018view →
STADDFSTertileIV0.0830.379.0019view →
SARCDFSTertileAll0.1300.632.0459view →
KIRCOSTertileAll0.4270.642.0326view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-273P–UCEC (OS)

Kaplan–Meier survival curve for RNU6-273P RNA-high vs -low samples in UCEC.

Open the UCEC breakdown →

Exploration