RNU6-271P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-271P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-271P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-271P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-271P expression acts as an unfavorable survival marker.

BRCA, LUAD, and SKCM are the cancer types where RNU6-271P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.8680.963<.001108view →
LUADDFSTertileIV0.0450.717<.00172view →
SKCMOSTertileAll0.1530.781<.00172view →
KIRCDFSTertileIV0.0920.620.00236view →
KIRPDFSTertileIV0.0880.502<.00136view →
GBMOSTertileAll0.1360.432.00127view →
UCECOSTertileIII,IV0.6410.835.03024view →
COADOSTertileIV0.2340.654.0499view →
LUSCOSTertileAll0.2220.413.0493view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration