RNU6-268P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-268P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-268P data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher RNU6-268P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-268P expression acts as an unfavorable survival marker, although some lineages such as LUAD and CESC show a favorable association.

READ, UVM, and LIHC are the cancer types where RNU6-268P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
READOSTertileAll0.5090.925<.00169view →
UVMDFSTertileIII,IV0.0790.674.02054view →
LIHCOSTertileAll0.3690.790<.00154view →
THCADFSTertileII,III,IV0.5000.898.00133view →
PAADDFSTertileIII,IV0.1180.734.01427view →
KIRCOSTertileAll0.4840.677.01624view →
THYMDFSTertileAll0.6580.916.00518view →
DLBCOSTertileII,III,IV0.1150.839<.00118view →
UCECDFSTertileAll0.6840.846.00718view →
PCPGOSTertileAll0.5160.947.00918view →
LUADOSTertileAll0.5060.328.01915view →
SKCMOSTertileIV0.1790.727<.00112view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration