RNU6-264P

Across TCGA pan-cancer cohorts, RNU6-264P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-264P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU6-264P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-264P expression acts as an unfavorable survival marker, although some lineages such as ESCA and GBM show a favorable association.

TGCT, KIRC, and MESO are the cancer types where RNU6-264P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	All	0.803	0.991	<.001	96	view →
KIRC	OS	Tertile	II,III,IV	0.556	0.719	.001	72	view →
MESO	OS	Tertile	All	0.052	0.528	.016	54	view →
UVM	OS	Tertile	All	0.220	0.917	<.001	54	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	36	view →
COAD	OS	Tertile	IV	0.045	0.659	<.001	36	view →
THCA	DFS	Tertile	II,III,IV	0.103	0.702	<.001	30	view →
PAAD	DFS	Tertile	All	0.118	0.468	.012	27	view →
DLBC	OS	Tertile	II,III,IV	0.421	0.771	.024	23	view →
BLCA	DFS	Tertile	All	0.253	0.608	.004	18	view →
LGG	DFS	Tertile	All	0.532	0.746	.006	15	view →
ESCA	OS	Quartile	III,IV	0.731	0.355	.011	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU6-264P–TGCT (OS)

Open the TGCT breakdown →