RNU6-256P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-256P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU6-256P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RNU6-256P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-256P expression acts as an unfavorable survival marker, although some lineages such as UCS show a favorable association.

LIHC, UCS, and BRCA are the cancer types where RNU6-256P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCOSTertileAll0.0410.781<.001108view →
UCSDFSTertileIII,IV1.0000.156.00178view →
BRCADFSTertileAll0.3210.903<.00136view →
KIRCDFSTertileAll0.2600.796.01236view →
LUADOSTertileAll0.0350.812<.00136view →
OVOSTertileII,III,IV0.6280.845.02118view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RNU6-256P–LIHC (OS)

Kaplan–Meier survival curve for RNU6-256P RNA-high vs -low samples in LIHC.

Open the LIHC breakdown →

Exploration