Across TCGA pan-cancer cohorts, RNU6-255P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNU6-255P data layer.
The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU6-255P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-255P expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.
TGCT, BLCA, and KIRC are the cancer types where RNU6-255P RNA most reproducibly stratifies survival.