RNU6-255P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-255P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNU6-255P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU6-255P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-255P expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

TGCT, BLCA, and KIRC are the cancer types where RNU6-255P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
TGCTOSTertileAll0.8390.975<.00190view →
BLCAOSTertileIV0.1950.484.02436view →
KIRCDFSTertileII,III,IV0.0700.762<.00136view →
SKCMDFSTertileAll0.9130.715.02212view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RNU6-255P–TGCT (OS)

Kaplan–Meier survival curve for RNU6-255P RNA-high vs -low samples in TGCT.

Open the TGCT breakdown →

Exploration