RNU6-24P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-24P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU6-24P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU6-24P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-24P expression acts as an unfavorable survival marker, although some lineages such as STAD and LAML show a favorable association.

THCA, ACC, and DLBC are the cancer types where RNU6-24P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCAOSTertileIV0.2521.000<.00136view →
ACCOSTertileIII,IV0.2370.626.00130view →
DLBCOSTertileAll0.0530.936<.00118view →
STADOSQuartileAll0.7670.619.02116view →
LAMLDFSMedianAll0.6920.491.02216view →
READOSTertileII,III,IV1.0000.544.03515view →
ESCADFSQuartileIV0.8260.277.04912view →
OVOSTertileII,III,IV0.9240.830.02412view →
LUSCDFSTertileAll0.2170.520.02112view →
PRADOSTertileAll0.9190.992<.00112view →
KIRPOSTertileAll0.7890.950.0333view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

Exploration