RNU6-247P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-247P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RNU6-247P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RNU6-247P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-247P expression acts as an unfavorable survival marker, although some lineages such as UCS and CESC show a favorable association.

UCS, KICH, and UVM are the cancer types where RNU6-247P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCSDFSMedianII,III,IV0.5490.172.00156view →
KICHOSTertileII,III,IV0.4080.844<.00145view →
UVMDFSTertileAll0.2810.769.00636view →
LUSCOSTertileIV0.0570.786.00836view →
CESCDFSTertileIV0.8080.099.00136view →
COADOSTertileIV0.0890.676<.00127view →
LUADDFSMedianIV0.7450.254.01020view →
LIHCOSTertileAll0.8290.606.01718view →
READDFSTertileIV0.0820.619.00118view →
SKCMOSTertileIII,IV0.6110.807.02715view →
BLCAOSTertileIV0.2500.657<.00112view →
MESOOSTertileIV0.8450.293.0329view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

Exploration