RNU6-241P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-241P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-241P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-241P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-241P expression acts as an unfavorable survival marker.

BLCA, CESC, and ESCA are the cancer types where RNU6-241P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSTertileIII,IV0.2310.551<.00181view →
CESCOSTertileIII,IV0.0910.755<.00172view →
ESCAOSTertileIV0.0950.512.00836view →
LUADOSTertileAll0.1410.788<.00136view →
LAMLDFSTertileAll0.1720.504.00636view →
STADOSTertileII,III,IV0.5030.734.03130view →
LUSCOSTertileAll0.3520.728.02318view →
TGCTOSTertileAll0.8170.968.02718view →
SKCMOSTertileAll0.3070.786.0259view →
COADOSTertileAll0.6990.870.0373view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration