RNU6-238P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-238P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU6-238P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-238P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-238P expression acts as an unfavorable survival marker, although some lineages such as STAD and HNSC show a favorable association.

MESO, STAD, and KIRC are the cancer types where RNU6-238P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESOOSTertileIII,IV0.1810.602<.00184view →
STADOSQuartileII,III,IV0.9160.526.00180view →
KIRCOSMedianAll0.4890.706<.00160view →
KICHDFSTertileIII,IV0.0430.774.00548view →
LIHCOSTertileIII,IV0.1440.550.00933view →
ACCOSTertileIII,IV0.2760.622.01018view →
SKCMDFSTertileIV0.0360.433<.00118view →
CESCOSTertileIV0.2780.647.01918view →
HNSCDFSTertileIV0.6600.516.03212view →
COADOSTertileIII,IV0.5070.805.0349view →
PAADDFSTertileIII,IV0.1520.821.0459view →
GBMOSTertileAll0.5280.293.0496view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration