RNU6-237P

Across TCGA pan-cancer cohorts, RNU6-237P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNU6-237P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU6-237P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-237P is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

BRCA, THCA, and KIRC are the cancer types where RNU6-237P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-237P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.206	.018	4	view →
THCA	Female	All	−0.343	.002	3	view →
KIRC	All	All	+0.182	.015	3	view →
CHOL	All	All	+1.003	.001	2	view →
COAD	Female	IV	+2.025	.043	1	view →
LIHC	All	III,IV	−0.238	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RNU6-237P–BRCA

Open the BRCA breakdown →