RNU6-236P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-236P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-236P data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher RNU6-236P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-236P expression acts as an unfavorable survival marker, although some lineages such as OV and BLCA show a favorable association.

PAAD, UCEC, and LIHC are the cancer types where RNU6-236P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PAADDFSTertileAll0.2500.494.00227view →
UCECDFSTertileII,III,IV0.5960.754.03224view →
LIHCDFSTertileIII,IV0.0770.414.00418view →
KICHDFSTertileIII,IV0.0430.897.04518view →
MESODFSTertileIII,IV0.1890.435.00618view →
SKCMOSTertileAll0.2170.349.00118view →
THCAOSTertileIV0.7201.000.00415view →
OVDFSTertileIII,IV0.4350.354.03412view →
PRADOSTertileAll0.9040.996<.00112view →
KIRCOSTertileAll0.4550.660.03210view →
COADDFSTertileIV0.0350.501<.0019view →
THYMDFSTertileAll0.4180.785.0256view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration