Across TCGA patient cohorts, RNU6-22P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,271 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-22P-associated GO terms across cancer lineages are Methylation, Macromolecule methylation, and Positive regulation of DNA repair. Each is linked with RNU6-22P in more than 11 cancer types. Because this analysis shows association rather than direction, both RNU6-22P-to-partner and partner-to-RNU6-22P results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-22P→partner) and Y-score (partner→RNU6-22P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Methylation →	+0.052	+0.642	.001	<.001	3	12
ESCA	Macromolecule methylation →	+0.055	+0.575	.002	<.001	3	12
STAD	Positive regulation of DNA repair →	+0.045	+0.491	<.001	<.001	3	11
ESCA	Negative regulation of gene expression, epigenetic →	+0.060	+0.588	.002	<.001	3	11
ESCA	Regulation of transcription by RNA polymerase I →	+0.067	+0.578	.003	<.001	2	12
ESCA	tRNA metabolic process →	+0.057	+0.555	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,271 associations by consensus.

Exploration

RNU6-22P survival (RNA) · tumor vs normal (RNA) · all RNU6-22P data types