RNU6-229P

Across TCGA patient cohorts, RNU6-229P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,280 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-229P-associated GO terms across cancer lineages are Positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway, Organelle membrane fusion, and Negative regulation of DNA-binding transcription factor activity. Each is linked with RNU6-229P in more than 7 cancer types. Because this analysis shows association rather than direction, both RNU6-229P-to-partner and partner-to-RNU6-229P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway grouped by RNU6-229P-low versus RNU6-229P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-229P→partner) and Y-score (partner→RNU6-229P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway →	+0.092	+0.259	<.001	<.001	3	8
ESCA	Organelle membrane fusion →	+0.122	+0.223	<.001	.001	3	8
ESCA	Negative regulation of DNA-binding transcription factor activity →	+0.107	+0.372	<.001	.002	3	8
ESCA	Regulation of epithelial cell migration →	+0.110	+0.203	<.001	.003	3	8
ESCA	Hematopoietic progenitor cell differentiation →	+0.104	+0.184	<.001	.008	3	8
STAD	Negative regulation of protein-containing complex assembly →	+0.106	+0.259	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,280 associations by consensus.

Positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway by RNU6-229P expression — STAD

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