RNU6-224P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-224P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU6-224P data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher RNU6-224P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-224P expression acts as an unfavorable survival marker.

STAD, LIHC, and UCEC are the cancer types where RNU6-224P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADDFSTertileII,III,IV0.3640.652<.001135view →
LIHCOSTertileAll0.1050.786<.00181view →
UCECDFSTertileAll0.0800.647<.00148view →
BLCADFSTertileAll0.1270.627<.00127view →
ESCAOSTertileII,III,IV0.3210.685.0359view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration