RNU6-196P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-196P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNU6-196P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-196P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-196P expression acts as an unfavorable survival marker, although some lineages such as BRCA and MESO show a favorable association.

ACC, READ, and STAD are the cancer types where RNU6-196P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSTertileAll0.5970.932<.00163view →
READDFSTertileIII,IV0.3560.779<.00148view →
STADDFSMedianII,III,IV0.4120.623<.00140view →
UVMDFSTertileIII,IV0.2440.698<.00135view →
LGGDFSMedianAll0.7760.873<.00135view →
BRCAOSQuartileIII,IV0.7560.421.00428view →
MESOOSTertileII,III,IV0.6940.515.02227view →
KIRPDFSQuartileAll0.5120.774<.00125view →
TGCTDFSTertileII,III,IV0.6380.996.00522view →
COADOSTertileIV1.0000.390.00221view →
CHOLOSTertileII,III,IV0.0240.601.02518view →
UCECDFSTertileAll0.3030.683.00618view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration