Across TCGA pan-cancer cohorts, RNU6-195P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU6-195P’s most consistent transcriptional readouts.

The strongest signal is observed in rectum adenocarcinoma (READ), where RNU6-195P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-195P is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.

READ, CHOL, and PRAD are the cancer types where RNU6-195P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-195P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
READ	Male	All	−0.713	.001	4	view →
CHOL	All	All	+0.864	.004	2	view →
PRAD	All	All	+0.341	.016	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RNU6-195P RNA expression & survival · all RNU6-195P data types