RNU6-190P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-190P RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated RNU6-190P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-190P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-190P expression acts as an unfavorable survival marker, although some lineages such as READ and LAML show a favorable association.

KIRC, READ, and KICH are the cancer types where RNU6-190P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSMedianAll0.5610.692<.001134view →
READOSMedianII,III,IV0.7510.456.00652view →
KICHDFSQuartileAll0.5590.930<.00132view →
THCAOSTertileAll0.7961.000.00431view →
COADDFSMedianAll0.6110.741.01119view →
UVMDFSQuartileAll0.3100.647.01718view →
SARCOSMedianAll0.3710.601.00917view →
MESODFSMedianII,III,IV0.3040.438.01814view →
LUADDFSQuartileIV0.2630.712.03312view →
LAMLDFSQuartileAll0.5510.206.00910view →
PCPGOSMedianAll0.9391.000.02510view →
ESCADFSMedianII,III,IV1.0000.452.0239view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

Exploration