RNU6-189P

Across TCGA pan-cancer cohorts, RNU6-189P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-189P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-189P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-189P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

KIRC, READ, and THCA are the cancer types where RNU6-189P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.226	0.649	<.001	141	view →
READ	OS	Tertile	II,III,IV	0.111	0.919	<.001	135	view →
THCA	DFS	Tertile	All	0.364	0.836	<.001	90	view →
SKCM	OS	Tertile	IV	0.297	0.777	<.001	48	view →
BLCA	OS	Tertile	IV	0.063	0.576	<.001	18	view →
KIRP	DFS	Tertile	II,III,IV	0.122	0.626	.032	18	view →
ESCA	DFS	Quartile	III,IV	0.477	0.249	.039	12	view →
OV	OS	Tertile	All	0.777	0.847	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU6-189P–KIRC (DFS)

Open the KIRC breakdown →