RNU6-179P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-179P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-179P data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher RNU6-179P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-179P expression acts as an unfavorable survival marker, although some lineages such as SARC and LUAD show a favorable association.

CESC, THCA, and THYM are the cancer types where RNU6-179P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CESCDFSTertileII,III,IV0.0530.786<.00196view →
THCADFSTertileAll0.3610.835<.00154view →
THYMOSTertileIII,IV0.1030.944<.00154view →
BLCAOSTertileAll0.1550.592.01236view →
DLBCOSTertileII,III,IV0.1180.802.02521view →
HNSCOSTertileIII,IV0.0860.674.00418view →
ESCADFSQuartileAll0.3660.544.01016view →
KIRCOSTertileAll0.4980.640.02312view →
STADDFSTertileIV0.0830.379.0019view →
SARCOSTertileAll0.9710.822.0126view →
LUADDFSTertileAll0.9240.794.0213view →
LGGOSTertileAll0.6450.466.0312view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration