RNU6-175P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-175P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-175P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-175P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-175P expression acts as an unfavorable survival marker.

BRCA, KIRC, and HNSC are the cancer types where RNU6-175P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCADFSTertileIII,IV0.3270.796.02436view →
KIRCDFSTertileIV0.2060.623.02118view →
HNSCOSTertileAll0.1670.710.00518view →
LAMLDFSTertileAll0.0280.583.00118view →
CESCOSTertileAll0.2710.798.01018view →
THCADFSTertileAll0.8250.935.0369view →
GBMOSTertileAll0.2030.422.0389view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNU6-175P–BRCA (DFS)

Kaplan–Meier survival curve for RNU6-175P RNA-high vs -low samples in BRCA.

Open the BRCA breakdown →

Exploration