RNU6-160P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-160P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU6-160P data layer.

The strongest signal is observed in thymoma (THYM), where higher RNU6-160P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-160P expression acts as an unfavorable survival marker, although some lineages such as ESCA and HNSC show a favorable association.

THYM, ESCA, and CESC are the cancer types where RNU6-160P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THYMOSTertileAll0.6040.975<.00190view →
ESCAOSQuartileIII,IV0.7630.326.00336view →
CESCDFSTertileIV0.2670.571.03518view →
TGCTDFSTertileII,III,IV0.5260.951.01118view →
SKCMOSTertileAll0.0810.392.01412view →
HNSCOSQuartileII,III,IV0.5120.321.00812view →
ACCDFSTertileAll0.1400.666.0499view →
LIHCDFSTertileII,III,IV0.0530.414.0069view →
STADOSTertileII,III,IV0.5340.727.0409view →
READDFSTertileIV0.2550.628.0209view →
LUADOSTertileAll0.2620.406.0493view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

Exploration