RNU6-157P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-157P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-157P data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RNU6-157P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-157P expression acts as an unfavorable survival marker.

KIRP, BRCA, and HNSC are the cancer types where RNU6-157P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRPDFSTertileII,III,IV0.0400.765<.001102view →
BRCAOSTertileIV0.2630.785.00372view →
HNSCOSTertileAll0.1740.710.01245view →
PAADOSTertileAll0.0940.640<.00136view →
THYMOSTertileAll0.6890.977.00236view →
LIHCOSTertileAll0.2460.673.01018view →
UCECDFSTertileAll0.6970.843.03212view →
STADDFSTertileIV0.0870.415<.0019view →
SARCOSTertileAll0.4400.869<.0019view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration