RNU6-155P

Across TCGA pan-cancer cohorts, RNU6-155P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-155P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-155P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-155P expression acts as an unfavorable survival marker, although some lineages such as COAD show a favorable association.

SKCM, MESO, and GBM are the cancer types where RNU6-155P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	II,III,IV	0.058	0.708	<.001	60	view →
MESO	DFS	Tertile	III,IV	0.043	0.415	<.001	54	view →
GBM	OS	Tertile	All	0.080	0.419	<.001	45	view →
CHOL	OS	Tertile	III,IV	0.024	0.772	.008	36	view →
READ	DFS	Tertile	All	0.255	0.844	.004	36	view →
TGCT	DFS	Tertile	III,IV	0.017	0.923	.021	24	view →
LAML	DFS	Tertile	All	0.167	0.597	<.001	18	view →
KIRC	DFS	Tertile	III,IV	0.199	0.489	.024	12	view →
PRAD	DFS	Tertile	All	0.768	0.892	.025	12	view →
DLBC	DFS	Tertile	III,IV	0.137	0.761	.014	9	view →
COAD	DFS	Tertile	All	0.871	0.438	.014	9	view →
LIHC	DFS	Tertile	All	0.228	0.557	.041	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-155P–SKCM (DFS)

Open the SKCM breakdown →